Membrane Cholesterol Regulates Smooth Muscle Phasic Contraction
نویسندگان
چکیده
منابع مشابه
Dynamics of smooth muscle contraction
Photolysis of caged calcium (Nitr5, Calbiochem®) can be used to studycalcium dependent processes such as excitation-contraction coupling andmuscular mechanics. Expensive high energy light sources are routinely used forUV light exposure; this study describes an alternative low cost Xenon flash unitconstmcted in our laboratOlY. A 300 J short arc Xenon flash lamp (Heimarl1l®)wa...
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Na-Ca exchange is proposed to be an important regulator of myoplasmic intracellular Ca concentration ([Ca]|) and contraction in vascular smooth muscle. We investigated the role of Na-Ca exchange in regulating [Ca], in swine carotid arterial tissues that were loaded with aequorin to allow simultaneous measurement of [Ca], and force. Reversal of Na-Ca exchange, by reduction of extracellular Na co...
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Excitation-contraction (EC) coupling in striated muscles is mediated by the cardiac or skeletal muscle isoform of voltage-dependent L-type Ca(2+) channel (Ca(v)1.2 and Ca(v)1.1, respectively) that senses a depolarization of the cell membrane, and in response, activates its corresponding isoform of intracellular Ca(2+) release channel/ryanodine receptor (RyR) to release stored Ca(2+), thereby in...
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ژورنال
عنوان ژورنال: Journal of Membrane Biology
سال: 2004
ISSN: 0022-2631,1432-1424
DOI: 10.1007/s00232-004-0663-1